From: Associations between selected immune-mediated diseases and tuberculosis: record-linkage studies
Immune-mediated disease (O and E for subsequent TB) | All time intervals: rate ratio (95% CI), Pvalue | At least 1 year after admission: rate ratio (95% CI), Pvalue | At least 5 years after admission: rate ratio (95% CI), Pvalue |
---|---|---|---|
Addison’s disease (85, 7.2) | 11.9 (9.5 to 14.7), <0.001 | 11.9 (8.4 to 16.3), <0.001 | 11.4 (6.9 to 17.6), <0.001 |
Ankylosing spondylitis (75, 18) | 4.2 (3.3 to 5.3), <0.001 | 4.1 (2.8 to 5.8), <0.001 | 3.9 (2.2 to 6.2), <0.001 |
Autoimmune hemolytic anemia (28, 5.5) | 5.1 (3.4 to 7.4), <0.001 | 4.9 (2.5 to 8.5), <0.001 | 4.0 (1.1 to 10.3), 0.013 |
Chronic active hepatitis (13, 2.9) | 4.5 (2.4 to 7.7), <0.001 | 5.6 (2.3 to 11.6), <0.001 | 5.8 (1.9 to 13.6), <0.001 |
Crohn’s disease (269, 76.1) | 3.7 (3.2 to 4.1), <0.001 | 2.8 (2.3 to 3.5), <0.001 | 2.1 (1.5 to 2.8), <0.001 |
Coeliac disease (79, 34.1) | 2.3 (1.9 to 2.9), <0.001 | 2.4 (1.6 to 3.3), <0.001 | 2.3 (1.4 to 3.7), <0.001 |
Dermatomyositis (9, 1.4) | 6.6 (3.0 to 12.5), <0.001 | 1.8 (0.1 to 9.9), 0.9 | 0.0 (0.0 to 10.3), 0.8 |
Polymyositis (21, 2.7) | 8.0 (4.9 to 12.2), <0.001 | 6.4 (2.8 to 12.7), <0.001 | 1.6 (0.0 to 8.8), 0.9 |
Goodpasture’s syndrome (6, 0.6) | 10.8 (4.0 to 23.5), <0.001 | 3.9 (0.1 to 21.7), 0.6 | 8.4 (0.2 to 47.0), 0.3 |
Hashimoto’s thyroiditis (9, 4) | 2.2 (1.0 to 4.3), 0.03 | 1.1 (0.1 to 4.0), 0.8 | 2.1 (0.3 to 7.4), 0.6 |
ITP (61, 17.7) | 3.5 (2.7 to 4.5), <0.001 | 2.4 (1.4 to 3.7), <0.001 | 2.4 (1.1 to 4.6), 0.02 |
Multiple sclerosis (40, 48.7) | 0.8 (0.6 to 1.1), 0.2 | 0.7 (0.4 to 1.2), 0.2 | 0.7 (0.3 to 1.3), 0.4 |
Myasthenia gravis (24, 9.1) | 2.6 (1.7 to 3.9), <0.001 | 2.1 (1.0 to 4.0), 0.04 | 0.5 (0.01 to 2.6), 0.6 |
Myxedema (843, 566.6) | 1.6 (1.5 to 1.7), <0.001 | 1.5 (1.4 to 1.7), <0.001 | 1.2 (1.0 to 1.5), 0.04 |
Pemphigus (2, 1.4) | 1.4 (0.2 to 5.0), 0.96 | 1.5 (0.0 to 8.3), 0.8 | 0.0 (0.0 to 11.8), 0.7 |
Pemphigoid (17, 8.4) | 2.0 (1.2 to 3.3), <0.001 | 1.8 (0.7 to 3.8), 0.2 | 1.5 (0.2 to 5.4), 0.9 |
Pernicious anemia (77, 40.8) | 1.9 (1.5 to 2.4), <0.001 | 2.1 (1.5 to 2.8), <0.001 | 1.2 (0.6 to 2.3), 0.7 |
Polyarteritis nodosa (10, 1.5) | 6.7 (3.2 to 12.4), <0.001 | 4.5 (0.9 to 13.1), 0.03 | 11.4 (3.1 to 29.4), <0.001 |
Primary biliary cirrhosis (24, 5.8) | 4.1 (2.6 to 6.1), <0.001 | 4.2 (2.1 to 7.6), <0.001 | 3.1 (0.9 to 8.1), 0.05 |
Psoriasis (177, 69.8) | 2.6 (2.2 to 3.0), <0.001 | 2.4 (1.9 to 3.0), <0.001 | 3.1 (2.2 to 4.1), <0.001 |
Rheumatoid arthritis (730, 249) | 3.2 (3.0 to 3.5), <0.001 | 3.0 (2.7 to 3.4), <0.001 | 3.0 (2.5 to 3.5), <0.001 |
Scleroderma (42, 6.9) | 6.1 (4.4 to 8.2), <0.001 | 5.3 (3.0 to 8.6), <0.001 | 5.0 (2.9 to 11.0), <0.001 |
Sjögren’s syndrome (46, 10.4) | 4.4 (3.2 to 5.9), <0.001 | 5.1 (3.2 to 7.6), <0.001 | 4.0 (1.8 to 7.6), <0.001 |
SLE (138, 15.1) | 9.4 (7.9 to 11.1), <0.001 | 9.1 (7.0 to 11.7), <0.001 | 9.1 (6.3 to 12.9), <0.001 |
Thyrotoxicosis (150, 74.8) | 2.0 (1.7 to 2.4), <0.001 | 2.2 (1.7 to 2.7), <0.001 | 1.4 (0.8 to 2.1), 0.2 |
Ulcerative colitis (204, 125.2) | 1.7 (1.4 to 1.9), <0.001 | 1.5 (1.2 to 1.8), 0.001 | 1.5 (1.1 to 2.0), 0.003 |