Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile

Table 4 Clinical variables associated with anti-Rib-P, anti-Sm and anti-dsDNA levels in patients with SLE

Variables	Anti-Rib-P^a		Anti-Sm^b		Anti-dsDNA^c
Variables	β coefficient	P	β coefficient	P	β coefficient	P
Ethnicity (Caucasian)	−0.190	0.034
CRP, mg/dl			0.304	0.003
Presence of serositis^d			0.321	0.002
Anti-RNP positive			0.297	0.003
Disease duration, years					−0.246	0.005
SLEDAI2K					0.338	<0.001
Presence of renal disorder^d					0.252	0.004

Abbreviations: Anti-dsDNA, anti-double-stranded DNA; anti-Rib-P, anti-ribosomal P; anti-RNP: anti-ribonucleoprotein; anti-Sm, anti-Smith; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate; SLE, systemic lupus erythematosus; SLEDAI2K: Systemic Lupus Erythematosus Disease Activity Index 2000. Multivariate analysis results from multiple linear regression analysis. The total explained variance of the model was ^a R ² = 0.036, ^b R ² = 0.325, and ^c R ² = 0.270. ^dIn accordance with American College of Rheumatology classification criteria.

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