Figure 7

GFP ⁺ BM chimeric mice. a-c) Chimeric mice injected intramuscularly with FLBs showed GFP⁺ BM-derived cells enclosing FLBs among inflammatory cells extracted from the injected muscle (a) at d4 after FLB injection, in spleen (b) and brain (c) at d33 after FLB injection. d-e) Chimeric mice showed incorporation of GFP⁺ cells in the brain, mainly in the form of perivascular cells in the cortex (d) and, occasionally, in more deeply located ramified CD11b⁺ cells (e, arrow) at d180 post-BM transplantation. (bars: 10 μm). BM, bone marrow; d, day; FLB, fluorescent latex beads.