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Figure 2 | BMC Medicine

Figure 2

From: Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets

Figure 2

Impact of palmitate treatment on insulin secretion and apoptosis in human pancreatic islets. a) Glucose-stimulated insulin secretion represented as fold change of insulin secretion (insulin secretion at high glucose levels/insulin secretion at low glucose levels) from human islets (n = 9) exposed to palmitate or control treatment for 48 h. A Wilcoxon one-tailed test was used. *P ≤0.05. b) Combined activity of Caspase-3/-7 as a measure of apoptosis in human islets (n = 4) exposed to palmitate or control treatment for 48 h. A Wilcoxon test was performed.

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