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Table 3 Factors associated with survival of all patients

From: Induction therapy with bortezomib and dexamethasone followed by autologous stem cell transplantation versus autologous stem cell transplantation alone in the treatment of renal AL amyloidosis: a randomized controlled trial

Factors

Univariate

Multivariate

HR

95% CI

P

HR

95% CI

P

Without BD induction

4.730

1.003-22.307

0.050

4.359

0.913-20.823

0.065

Urine protein >3.5 g/24 hour

1.2

0.310-4.647

0.792

   

Cardiac stage III

4.118

1.138-14.899

0.031

1.272

0.276-5.864

0.758

Baseline BNP >170 ng/L

2.837

0.814-9.892

0.104

   

Troponin-I >0.03

6.494

1.673-25.213

0.007

6.138

1.559-24.170

0.009

The use of MEL 140

3.445

0.730-16.255

0.118

   
  1. BD, bortezomib in combination wity dexamethasone; BNP, brain natriuretic peptide; CI, confidence interval; HR, hazard ratio; MEL, melphalan.
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BMC Medicine

ISSN: 1741-7015

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