Table 1 Clinical and analytical features of patients and healthy controls
Patients with celiac disease | Patients with autoimmune disease | Healthy controls n = 200 | |
|---|---|---|---|
n = 383 | n = 428 | ||
Gender (female/male) | 241/142 | 280/148 | 112/88 |
Mean age (SD) | 22 (21.76) | 39 (23.04) | 23 (18.74) |
Biopsy | |||
Marsh I | 7 (1.8%) | - | - |
Marsh II | 32 (8.3%) | - | - |
Marsh IIIa | 63 (16.4%) | - | - |
Marsh IIIb | 70 (18.3%) | - | - |
Marsh IIIc | 211 (55.1%) | - | - |
HLA-DQ2-positivea | 338 (89.2%)b | 182 (42%) | 44 (22%) |
HLA-DQ8-positivea | 42 (11.0%) | 152 (35%) | 18 (9%) |
HLA-DQ2 and DQ8-negative | 14 (3.6%) | 136 (31.8%) | 138 (69%) |
Autoimmune diseases | 58 (15.1%) | 428 (100%) | - |