Verbal autopsy as a tool for identifying children dying of sickle cell disease: a validation study conducted in Kilifi district, Kenya

Table 2 Validation results for the InterVA-4 model and PCVA consensus against the pediatric ward COD for the top ten CODs among 134 child deaths

Cause of death	Sensitivity, %		Specificity, %		PPV%		NPV%
	InterVA-4	PCVA consensus	InterVA-4	PCVA consensus	InterVA-4	PCVA consensus	InterVA-4	PCVA consensus
1.05: Malaria	80	83	83	90	38	50	97	97
1.02: Pneumonia	14	28	94	91	14	41	81	85
3.02: Severe malnutrition	10	47	97	91	10	44	87	92
98: Other unspecified non-communicable disease	9	18	100	92	100	17	92	93
10.06: Congenital malformation	55	73	98	98	67	73	96	98
1.07: Meningitis	12	44	91	94	15	33	93	96
1.03: HIV/AIDS	40	43	88	95	18	24	94	93
1.04: Diarrheal diseases	29	29	96	98	29	40	96	96
4.03: Sickle cell with crisis	83	83	99	98	83	63	99	99

NPV, negative predicted value; PCVA, physician coded verbal autopsy; PPV, positive predictive value.

ISSN: 1741-7015