Predictive score for mortality in patients with COPD exacerbations attending hospital emergency departments

Table 4 Comparison of different prediction scales on short-term mortality on patients with eCOPD

Outcome	N	Short-term mortality		Pvalue*	AUC	95% CI	Pvalue**
		Yes	No
DeCOPD score mean (sd)	2484	9.03 (4.27)	3.07 (3.4)	≤0.0001	0.85	0.79 to 0.90	Ref^a
DeCOPD score (categorical)	2484			≤0.0001	0.84	0.79 to 0.89	0.38
Risk
Mild	1081	3 (0.28)	1078 (99.72)
Moderate	865	11 (1.27)	854 (98.73)
Severe	441	20 (4.54)	421 (95.46)
Very severe	97	24 (24.74)	73 (75.26)
GOLD FEV1%	2069			0.0133	0.62	0.56 to 0.69	<0.0001
FEV1% ≥80	76	0 (0.0)	76 (100)
50 ≤ FEV1% <80	643	6 (0.93)	637 (99.07)
30 ≤ FEV1% <50	959	28 (2.92)	931 (97.08)
FEV1% ≤30	391	13 (3.32)	378 (96.68)
GOLD COPD combined assessment	2090			<0.002	0.71	0.67 to 0.75	<0.0001
Low risk, low symptom burden	286	1 (0.35)	285 (99.65)
Low risk, higher symptom burden	335	4 (1.19)	331 (98.81)
High risk, low symptom burden	351	0 (0.00)	351 (100)
High risk, higher symptom burden	1118	46 (4.11)	1072 (95.89)
HADO score	1887			0.0002	0.68	0.63 to 0.72	<0.0001
Mild (<4)	188	0	188 (100)
Moderate (5 to 7)	604	3 (0.50)	601 (99.50)
Severe (>8)	1095	33 (3.01)	1062 (96.99)
ADO index (0 to 14) mean (sd)	2067	11.36 (1.71)	9.29 (2.19)	≤0.0001	0.78	0.71 to 0.84	0.05

Abbreviations: ADO age, baseline dyspnea, and airflow obstruction; AUC, area under the curve; COPD, chronic obstructive pulmonary disease; DeCOPD, Death in exacerbation of chronic obstructive pulmonary disease; ED, emergency department; FEV, forced expiratory volume; GOLD, Global Initiative for Chronic Obstructive Lung Disease; HADO, health, activity, dyspnea, and airflow obstruction; LTHOT; long-term home oxygen therapy; MRC, Medical Research Council; NIMV, non-invasive mechanical ventilation; PCO₂ carbon dioxide partial pressure; PO₂, oxygen partial pressure.
^aReference value.
*p-value of the relationship of each parameter with short-term mortality.
**p-value or the comparison of areas under Receiver Operating Characteristic Curves with respect to the AUC of the DECOPD continuous scale.

ISSN: 1741-7015