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Table 4 Comparison of different prediction scales on short-term mortality on patients with eCOPD

From: Predictive score for mortality in patients with COPD exacerbations attending hospital emergency departments

Outcome N Short-term mortality Pvalue* AUC 95% CI Pvalue**
   Yes No     
DeCOPD score mean (sd) 2484 9.03 (4.27) 3.07 (3.4) ≤0.0001 0.85 0.79 to 0.90 Refa
DeCOPD score (categorical) 2484    ≤0.0001 0.84 0.79 to 0.89 0.38
Risk        
Mild 1081 3 (0.28) 1078 (99.72)     
Moderate 865 11 (1.27) 854 (98.73)     
Severe 441 20 (4.54) 421 (95.46)     
Very severe 97 24 (24.74) 73 (75.26)     
GOLD FEV1% 2069    0.0133 0.62 0.56 to 0.69 <0.0001
FEV1% ≥80 76 0 (0.0) 76 (100)     
50 ≤ FEV1% <80 643 6 (0.93) 637 (99.07)     
30 ≤ FEV1% <50 959 28 (2.92) 931 (97.08)     
FEV1% ≤30 391 13 (3.32) 378 (96.68)     
GOLD COPD combined assessment 2090    <0.002 0.71 0.67 to 0.75 <0.0001
Low risk, low symptom burden 286 1 (0.35) 285 (99.65)     
Low risk, higher symptom burden 335 4 (1.19) 331 (98.81)     
High risk, low symptom burden 351 0 (0.00) 351 (100)     
High risk, higher symptom burden 1118 46 (4.11) 1072 (95.89)     
HADO score 1887    0.0002 0.68 0.63 to 0.72 <0.0001
Mild (<4) 188 0 188 (100)     
Moderate (5 to 7) 604 3 (0.50) 601 (99.50)     
Severe (>8) 1095 33 (3.01) 1062 (96.99)     
ADO index (0 to 14) mean (sd) 2067 11.36 (1.71) 9.29 (2.19) ≤0.0001 0.78 0.71 to 0.84 0.05
  1. Abbreviations: ADO age, baseline dyspnea, and airflow obstruction; AUC, area under the curve; COPD, chronic obstructive pulmonary disease; DeCOPD, Death in exacerbation of chronic obstructive pulmonary disease; ED, emergency department; FEV, forced expiratory volume; GOLD, Global Initiative for Chronic Obstructive Lung Disease; HADO, health, activity, dyspnea, and airflow obstruction; LTHOT; long-term home oxygen therapy; MRC, Medical Research Council; NIMV, non-invasive mechanical ventilation; PCO2 carbon dioxide partial pressure; PO2, oxygen partial pressure.
  2. aReference value.
  3. *p-value of the relationship of each parameter with short-term mortality.
  4. **p-value or the comparison of areas under Receiver Operating Characteristic Curves with respect to the AUC of the DECOPD continuous scale.