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Table 2 Volume, timing and additional transfusion by study arm

From: Phase II trial of standard versus increased transfusion volume in Ugandan children with acute severe anemia

 

Arm A: 20 ml/kg (Number = 82)

Arm B: 30 ml/kg (Number = 78)

Pvalue

Volume of initial transfusiona (ml/kg) – median (IQR)

20 (20 to 20)

30 (30 to 30)

<0.0001

Rate of initial transfusiona (ml/kg/hr) – median (IQR)

5.7 (4.9 to 6.7)

7.6 (6.1 to 8.4)

<0.0001

Time to initial transfusion (minutes) – median (IQR)

95 (75 to 128)

103 (75 to 130)

0.74

Total volume tranfused 0 to 48 hours (ml/kg) – median (IQR)

20 (20 to 20)

30 (30 to 30)

<0.0001

Number of transfusionsb per child 0 to 48 hours, number (%)

  

0.23

 1

67 (82)

69 (88)

 2

14 (17)

8 (10)

 3

0 (0)

1 (1)

 4

1 (1)

0(0)

Number of children with a transfusion after 48 hours

2

1

 
  1. aRefers to blood infused before the first 30-minute break between aliquots of blood. This was the entire initial prescription for all but three children (all 30 ml/kg arm) where the last aliquot was given 49, 64, and 92 minutes after the previous aliquot; brefers to the number of prescriptions. IQR, interquartile range.