Phase II trial of standard versus increased transfusion volume in Ugandan children with acute severe anemia

Table 4 Serious adverse events (including fatal events)

SAE	Arm A: 20 ml/kg (Number = 82)	Arm B: 30 ml/kg (Number = 78)	Total
Clinician defined SAEs
Allergic reaction/transfusion reaction	0	1^a	1
Deaths
Cardio respiratory arrest	1	0	1
Respiratory arrest	1	0	1
Multiple organ failure	0	1^b	1
Other deaths	4	0	4
Total	6	2	8
Adjudication by endpoint committee
Fatal events relationship to transfusion ^c
Definitely	0	-
Probably	0	-
Possibly	3	-
Not related	3	1^b
unknown	0	-

^aMedian rate of transfusion at the time of reaction, 0.95 ml/minute, no events judged to have any relationship to volume of transfusions; ^boccurred four days after discharge (day 12 post-admission); ^csee Table S1 in Additional file 2 for further details of the deaths.