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Table 5 IRR: one-way sensitivity analyses

From: Estimating the returns to UK publicly funded cancer-related research in terms of the net value of improved health outcomes

Analysis IRR, %
Base casea 10.1
Research funding estimate  
  Low 10.8
  High 8.7
‘Value’ of a QALY, GB£  
  20,000 8.0
  30,000 11.7
  50,000 16.1
  70,000 18.9
Elapsed time, years  
  10 14.6
  20 7.4
Attribution to UK research, %  
  10 6.1
  25 13.0
Effect of smoking cessation  
  Decrease NMB by 25% 8.7
  Increase NMB by 25% 11.2
  Omitting benefit of smoking reduction 2.4
  1. Abbreviations: IRR internal rate of return, NMB net monetary benefits, QALY quality adjusted life year.
  2. aBest estimate for research funding and net monetary benefit, QALY value of £25,000, elapsed time of 15 years, and attribution to UK research of 17%).