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Table 3 Quantitative gene (mRNA) expression data in ventricular samples from a background of no cardiac disease (Control), idiopathic cardiomyopathy (IDC) and ischemic cardiomyopathy (ICM).

From: ACE2 gene expression is up-regulated in the human failing heart

Target Copy number with 95% CI
  Control (n = 9) IDC (n = 11) Δ from Control ICM (n = 12) Δ from Control
ACE2 3,978 (2,102–5,531) 9,612† (5,873–15,734) 2.4 7,338† (5,304–10,153) 1.8
ACE 720 (349–1,484) 2,239† (1,343–3,735) 3.1 1,692† (1,295–2,211) 2.4
ANF 19,547 (4,377–87,287) 248,243† (57,940–10,635,486) 12.7 151,551 (57,743–397,759) 7.8
AT 1 623 (456–850) 594 (347–1,020) 0.95 541 (352–829) 0.87
RENIN 0 0   0  
  1. Values are geometric mean copy number for each gene/100 ng total RNA. † – P < 0.05 disease group Vs. Control.