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Table 1 Distribution of MTHFR C677T (genotype and allele) frequencies in unrelated migraine and control groups.

From: The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura

 

Genotypes

 

Alleles

Group

C/C

C/T

T/T

N (genotypes)

C

T

MO+MA

104 (39%)

125 (46%)

39 (15%)

268

333 (62%)

203 (38%)

MA*

64 (38%)

72 (43%)

32 (19%)

168

200 (60%)

136 (40%)

MO

40 (40%)

53 (53%)

7 (7%)

100

133 (66%)

67 (34%)

Control

117 (43%)

129 (48%)

23 (9%)

269

363 (67%)

175 (33%)

  1. *genotype distribution comparison (Trend χ2 = 5.72, P = 0.017), T/T genotype vs. C/C (OR = 2.54, 95% CI: 1.37 – 4.71).