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Table 1 Distribution of MTHFR C677T (genotype and allele) frequencies in unrelated migraine and control groups.

From: The methylenetetrahydrofolate reductase gene variant C677T influences susceptibility to migraine with aura

  Genotypes   Alleles
Group C/C C/T T/T N (genotypes) C T
MO+MA 104 (39%) 125 (46%) 39 (15%) 268 333 (62%) 203 (38%)
MA* 64 (38%) 72 (43%) 32 (19%) 168 200 (60%) 136 (40%)
MO 40 (40%) 53 (53%) 7 (7%) 100 133 (66%) 67 (34%)
Control 117 (43%) 129 (48%) 23 (9%) 269 363 (67%) 175 (33%)
  1. *genotype distribution comparison (Trend χ2 = 5.72, P = 0.017), T/T genotype vs. C/C (OR = 2.54, 95% CI: 1.37 – 4.71).