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Table 2 Predictors of the presence of coronary artery calcium, in three logistic regression models

From: What does my patient's coronary artery calcium score mean? Combining information from the coronary artery calcium score with information from conventional risk factors to estimate coronary heart disease risk

Modeling approach Model results
Predictors Odds ratio (95% CI) p-value C-statistic
Age and sex only*    
   - Age, per 10 years 2.83 (2.67 – 2.99) <0.001 0.76
   - Male sex 3.60 (3.26 – 3.96) <0.001  
All CHD risk factors*    
   - Age, per 10 years 2.78 (2.62 – 2.94) <0.001 0.78
   - Male sex 3.67 (3.31 – 4.06) <0.001  
   - Hypertension 1.51 (1.37 – 1.66) <0.001  
   - Diabetes mellitus 1.85 (1.55 – 2.21) <0.001  
   - High cholesterol 1.40 (1.27 – 1.54) <0.001  
   - Smoking 1.71 (1.56 – 1.89) <0.001  
Estimated 10-year risk of CHD†, only*    
   - 10-year risk, per 5% increase in the Framingham 10-year CHD risk estimate 1.96 (1.88 – 2.04) <0.001 0.74
  1. * – Intercepts (on a log-odds scale) were -6.20, -6.76, and -1.44 for each model, respectively.
  2. † – 10-year risk of CHD estimated according to Framingham equations [16]; for assumptions used, see Methods.
  3. CHD – Coronary heart disease; CI – Confidence interval.