Skip to main content

Table 4 Estimated prevalence of a coronary artery calcium score in each of four standard categories, depending on the Framingham estimated 10-year risk of coronary heart disease events.

From: What does my patient's coronary artery calcium score mean? Combining information from the coronary artery calcium score with information from conventional risk factors to estimate coronary heart disease risk

Framingham 10-year CHD risk estimate* Estimated prevalence of a CAC score in the given range†, %
  0 1–100 101–400 >400
2.5% 75 19 4 1
5.0% 68 23 6 2
7.5% 61 28 8 3
10.0% 52 32 11 5
12.5% 44 36 13 7
15.0% 36 38 17 9
17.5% 29 40 19 12
20.0% 22 41 22 15
22.5% 17 40 25 18
25.0% 13 39 27 22
  1. * – 10-year risk of CHD events estimated according to equations derived from the Framingham study[16]. For assumptions, see Methods.
  2. † – Proportions of subjects in each given CAC score category were estimated by a two step process: 1) Logistic regression to predict the presence of CAC according to estimated 10-year risk (see Table 2 for model coefficients), and 2) Linear regression to predict the extent of CAC, as measured by the natural log-transformed CAC score (see Table 3 for model coefficients). Other values required for this calculation were the logistic regression constant (-1.44), the linear regression constant (3.17), and the standard deviation of the residuals after linear regression (1.707).
  3. CAC – Coronary artery calcium; CHD – Coronary heart disease.