Table 2 Model Parameters
From: Age-related human small intestine methylation: evidence for stem cell niches
Parameter | Stem Cell Niche | Immortal Lineages |
|---|---|---|
Stem Cells per Crypt | 4–256 | 2 |
Probability of Asymmetric Stem Cell Division (P1)* | 0.98 to 0.89 | 1.0 |
Probability of Symmetric Stem Cell Division: zero (P0) or two (P2) stem cell offspring* | 0.02 to 0.11 | 0 |
Methylation Error Rate | 2 × 10-5 per CpG site per division** | 2 × 10-5 per CpG site per division** |
Stem Cell Division Rate | 0.75 per day | 0.75 per day |