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Table 6 Medical Outcomes Study Short-Form 36 (SF-36), Multi-Dimensional Fatigue Inventory (MFI) and Symptom Inventory Scores according to current illness classified by standardized clinically empirical criteria in 164 participants with no exclusionary medical or psychiatric conditions.

From: Chronic Fatigue Syndrome – A clinically empirical approach to its definition and study

SF-36    
Scale CFS ISF Not Ill
Physical function+ 53.3 ± 21.5 * 77.5 ± 18.9 89.7 ± 13.2
Role physical+ 18.0 ± 28.5 * 60.7 ± 37.2 88.8 ± 25.0
Bodily pain 41.7 ± 15.7 * 59.7 ± 20.0 77.9 ± 16.0
General health 51.2 ± 20.4 * 70.1 ± 13.6 85.2 ± 13.3
Vitality 18.6 ± 12.5 * 37.3 ± 18.5 72.3 ± 13.0
Social function+ 50.0 ± 22.7 * 74.2 ± 19.6 94.8 ± 10.6
Role emotional+ 55.8 ± 42.2 * 76.5 ± 33.5 96.1 ± 13.8
Mental health 66.4 ± 18.5 * 74.6 ± 14.0 87.5 ± 9.0
MFI    
General fatigue+ 18.5 ± 2.1 * 14.9 ± 2.7 8.0 ± 2.6
Physical fatigue 14.1 ± 3.2 * 11.0 ± 3.2 6.8 ± 2.2
Mental fatigue 14.1 ± 4.2 * 10.0 ± 4.3 6.6 ± 2.6
Reduced motivation 12.2 ± 3.8 * 10.1 ± 3.3 6.1 ± 2.0
Reduced activity+ 14.7 ± 3.1 * 11.5 ± 4.0 5.6 ± 1.6
Symptom Inventory + 47.3 ± 22.0 * 18.6 ± 11.9 6.1 ± 7.1
  1. +Indicate subscales used in validated clinically empirical CFS case definition
  2. Scores are mean ± standard deviation
  3. Bolded figures indicate that specific group scores are significantly different (p < 0.05) from non-fatigued scores.
  4. * indicates that CFS scores are significantly different from ISF scores
  5. Note: Low scores in the SF-36 indicate more severe conditions, whereas in the MFI higher scores indicate more severe conditions.
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