Table 3 Baseline characteristics of patients who discontinued due to poor response or symptom worsening
Characteristic | Study 1 (n = 67) | Study 2 (n = 78) | Study 3 (n = 99) | Study 4 (n = 71) | Total (N = 315) |
|---|---|---|---|---|---|
Age (mean ± SD) | 36.17 ± 11.14 | 39.56 ± 9.36 | 38.58 ± 11.95 | 41.77 ± 9.91 | 39.03 ± 10.84 |
Sex (Male %) | 43(64.2) | 57(73.1) | 58(58.6) | 53(74.6) | 211(67.0) |
Race (Caucasian %)* | 54(80.6) | 48(61.5) | 53(53.5) | 48(67.6) | 203(64.4) |
Diagnosis (%) | |||||
Schizophrenia | 57(85.1) | 54(69.2) | 99(100) | 39(54.9) | 249(79.8) |
Schizoaffective | 8(11.9) | 24(30.8) | -- | 32(45.1) | 64(20.5) |
Schizophreniform | 2 (3.0) | -- | -- | -- | 2 (0.6) |
Age of Onset Illness (yrs ± SD) | 22.80 ± 6.69 | 21.63 ± 6.85 | 22.44 ± 7.62 | 22.63 ± 7.43 | 22.36 ± 7.18 |
PANSS Total (mean ± SD) | 95.48 ± 15.31 | 86.60 ± 15.60 | 105.83 ± 22.04 | 82.01 ± 16.82 | 93.50 ± 20.35 |
Prior Hospitalization (%)* | 65(97.0) | 45(57.7) | 27(27.3) | 42(59.2) | 179(56.8) |
Hospitalization days (mean ± SD)† | 35.75 ± 54.52 | 73.11 ± 113.67 | 24.96 ± 69.32 | 49.14 ± 50.12 | 46.66 ± 76.40 |
Illness Duration (yrs ± SD) | 13.25 ± 10.47 | 17.93 ± 9.53 | 16.13 ± 12.02 | 19.13 ± 10.83 | 16.65 ± 10.99 |