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Table 2 Effects of aspirin on collagen induced platelet aggregation and EC50 concentrations postoperatively (final – baseline)

From: Biological efficacy of low versus medium dose aspirin after coronary surgery: results from a randomized trial [NCT00262275]

  Baseline (SD) Final (SD) Difference (95% CI) P value
Percentage aggregation (using 1.1 μg/ml collagen)
Medium dose 70 (28) 32 (15) -37 (-46 to -28) <0.001
Low dose 76 (21) 39 (21) -36 (-46 to -27) <0.001
Mean EC50 concentration (using 0.11 – 4.4 μg/ml collagen)
Medium dose 0.53 (0.58) 1.79 (0.91) 1.23 (0.95 to 1.52) <0.001
Low dose 0.48 (0.51) 1.69 (1.10) 1.20 (0.80 to 1.59) <0.001
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