Table 2 Effects of aspirin on collagen induced platelet aggregation and EC50 concentrations postoperatively (final – baseline)
Baseline (SD) | Final (SD) | Difference (95% CI) | P value | |
|---|---|---|---|---|
Percentage aggregation (using 1.1 μg/ml collagen) | ||||
Medium dose | 70 (28) | 32 (15) | -37 (-46 to -28) | <0.001 |
Low dose | 76 (21) | 39 (21) | -36 (-46 to -27) | <0.001 |
Mean EC50 concentration (using 0.11 – 4.4 μg/ml collagen) | ||||
Medium dose | 0.53 (0.58) | 1.79 (0.91) | 1.23 (0.95 to 1.52) | <0.001 |
Low dose | 0.48 (0.51) | 1.69 (1.10) | 1.20 (0.80 to 1.59) | <0.001 |