Table 1 Demographic and clinical characteristics at baseline for patients with a major depressive episode (full analysis set)
Characteristic | WS® 5570 600 mg/day N = 119 | WS® 5570 1200 mg/day N = 124 | Placebo N = 81 | p-value | |
|---|---|---|---|---|---|
Sex: | 0.13* | ||||
Female | n (%) | 67 (56.3) | 82 (66.1) | 56 (69.1) | |
Male | n (%) | 52 (43.7) | 42 (33.9) | 25 (30.9) | |
Age (years) | Mean ± SD | 46.3 ± 11.5 | 46.1 ± 10.7 | 46.9 ± 11.8 | 0.69§ |
HAM-D total score | Mean ± SD | 22.8 ± 3.3 | 22.6 ± 3.8 | 23.6 ± 4.2 | 0.31 |
CGI severity of illness: | 0.20* | ||||
Mildly or moderately ill | n (%) | 67 (56.3) | 62 (50.0) | 46 (56.8) | |
Markedly or severely ill | n (%) | 52 (43.7) | 62 (50.0) | 35 (43.2) | |
MADRS | Mean ± SD | 27.2 ± 5.5 | 26.3 ± 6.0 | 28.0 ± 6.2 | 0.09§ |
BDI | Mean ± SD | 23.2 ± 7.9 | 23.3 ± 8.0 | 25.7 ± 8.9 | 0.05§ |
SF-36 summary measure mental health | Mean ± SD | 25.1 ± 11.7 | 27.7 ± 13.3 | 23.7 ± 11.1 | 0.16§ |