Table 1 Characteristics of the InCHIANTI study general population sample aged ≥ 65 years, and the subgroup with diabetes
From: Effects of the diabetes linked TCF7L2polymorphism in a representative older population
All subjects ≥ 65 years | Subjects with diabetes | |
|---|---|---|
Number of subjects | 944 | 127 |
Male | 415 (44%) | 64 (50%) |
Age (years) | 75 ± 7.4 | 74 ± 6.8 |
BMI | ||
< 25 kg/m2 | 251 (27%) | 23 (18%) |
25–29 kg/m2 | 395 (42%) | 52 (41%) |
30+ kg/m2 | 298 (32%) | 52 (41%) |
Subjects with abdominal obesity* | 343 (40%) | 60 (47%) |
Fasting glucose levels | ||
< 6 mmol/L | 774 (82%) | 31 (24%) |
6–6.9 mmol/L | 70 (7%) | 18 (14%) |
7+ mmol/L | 100 (11%) | 78 (61%) |
Insulin levels (pmol/L) | 68.6 ± 1.7 | 76.3 ± 1.7 |
HOMA beta cell function (%) | 107.7 ± 1.6 | 59.6 ± 1.9 |
HOMA insulin sensitivity (%) | 75.9 ± 1.6 | 62.7 ± 1.6 |
Total cholesterol (mg/dL) | 213.1 ± 1.2 | 205.3 ± 1.2 |
LDL (mg/dL) | 131.2 ± 1.3 | 124.7 ± 1.3 |
HDL (mg/dL) | 53.7 ± 1.3 | 49.2 ± 1.3 |
Triglycerides (mg/dL) | 114.1 ± 1.6 | 124.7 ± 1.7 |
rs7903146 genotypes | ||
CC | 394 (42%) | 49 (39%) |
CT | 439 (47%) | 57 (45%) |
TT | 111 (12%) | 21 (17%) |