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Table 4 Characteristics of patients with diabetes and ADA diagnosed hyperglycemia patients by TCF7L2 genotype

From: Effects of the diabetes linked TCF7L2polymorphism in a representative older population

  

Diabetes

Diabetes and impaired fasting glucose

 

Genotype

n

%

Age- and sex-adjusted OR

95% CI

p value

n

%

Age- and sex-adjusted OR

95%CI

p value

Two or more metabolic syndrome features

CC

33

73.3

   

56

66.7

   
 

CT/TT

41

58.6

0.37

0.15–0.92

0.033

78

55.7

0.55

0.30–0.99

0.047

High blood pressure or anti-hypertension drugs

CC

37

78.7

   

64

74.4

   
 

CT/TT

47

61.8

0.37

0.16–0.90

0.028

101

67.8

0.65

0.35–1.20

0.170

Abdominal obesity

CC

25

54.4

   

44

51.8

   
 

CT/TT

35

49.3

0.53

0.20–1.35

0.180

67

46.9

0.67

0.36–1.22

0.188

High triglycerides

CC

20

41.7

   

39

44.8

   
 

CT/TT

25

32.5

0.68

0.32–1.43

0.307

49

32.2

0.58

0.33–0.99

0.047

Low HDL levels

CC

17

35.4

   

31

35.6

   
 

CT/TT

26

33.8

0.83

0.37–1.86

0.651

44

29

0.67

0.37–1.21

0.185

Myocardial infarction

CC

7

14.6

   

8

9.2

   
 

CT/TT

2

2.6

0.16

0.03–0.84

0.030

4

2.6

0.27

0.08–0.92

0.037

Poor renal function (24-hour creatinine clearance)

CC

12

26.1

   

31

36.9

   
 

CT/TT

32

47.1

3.15

1.27–7.81

0.013

69

49.3

1.74

0.96–3.17

0.066

Retinopathy reported

CC

1

2.0

   

1

1.1

   
 

CT/TT

11

14.1

7.15

0.87–58.51

0.067

11

7.2

6.13

0.77–48.86

0.087

Dementia (physician diagnosed)

CC

1

2.0

   

1

1.1

   
 

CT/TT

8

10.3

10.67

1.00–113.70

0.050

13

8.5

11.62

1.38–97.57

0.024

  1. HDL, high-density lipoprotein.