Figure 3

Reorganization of marginal cells. Apical surface areas of marginal cells were measured using images of whole-mounts of stria vascularis as shown in Fig. 2. Frequency histograms (bin size 25 μm²) of surface area measurements were constructed. The number (n) of cells contributing to each histogram is given. Note that surface areas in Slc26a4 ^+/- mice of all ages were normally distributed and narrowly centered at ~ 100 μm². The distribution of surface areas in Slc26a4 ^-/- mice progressed during development from a distribution centered at ~ 240 μm² to a wide multimodal distribution with peaks centered at ~ 100 and ~ 240 μm².