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Table 3 Genes that were expected to be expressed in stria vascularis.

From: Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

    Slc26a4 +/+ Slc26a4 -/-   
No. Gene Description Intensity P Intensity P Fold Direction
1 Slc12a1 Na+/2Cl-/K+ cotransporter 14,664 12/12 10,656 12/12 1.33 down
2 Atp1a1 Na+/K+ ATPase, alpha 7,276 9/15 5,440 9/15 2.06 down
3 Atp1b1 Na+/K+ ATPase, beta1 10,593 12/18 8,587 12/18 1.20  
4 Atp1b2 Na+/K+ ATPase, beta2 8,057 6/6 5,984 6/6 1.41 down
5 Kcnq1 K+ channel, alpha 858 15/24 542 11/24 2.48 down
6 Kcne1 K+ channel, beta 9,042 6/6 3,490 6/6 2.60 down
7 Kcnma1 K+ channel, BK 270 10/18 159 9/18 1.72 down
8 Kcnk1 K+ channel 2,667 6/6 1,670 6/6 1.92 down
9 Slc26a4 Pendrin 1,136 3/3 619 3/3 1.84 down
10 Kcnj10 K+ channel 17,169 3/3 17,005 3/3 1.01  
11 Car2 Carbonic anhydrase 9,139 3/3 9,167 3/3 1.00  
12 Gjb2 Connexin 26 12,785 3/3 12,629 3/3 1.01  
13 Gjb6 Connexin 30 15,257 3/3 13,060 3/3 1.17  
14 Sod1 Superoxide dismutase 4,149 14/15 3,538 14/15 1.21  
15 Cat Catalase 3,520 6/6 4,686 6/6 1.12  
16 Gpx1 Glutathione peroxidase 2,633 3/3 4,320 3/3 1.64 up
17 Gpx3 Glutathione peroxidase 12,526 3/3 9,898 3/3 1.27  
18 Gpx4 Glutathione peroxidase 11,224 6/6 10,421 6/6 1.06  
19 Tyr Tyrosinase 3,520 6/6 4,686 6/6 1.16  
  1. Genes that are expected to be expressed in marginal and spindle cells of stria vascularis (1–9) and genes that are expected to be expressed in intermediate and basal cells of stria vascularis (10–19) are listed. For parameters 'P', 'Fold' and 'Direction', see the Gene array section in Methods. Fold changes are given when a gene was called Present (P) in Slc26a4 +/- or Slc26a4 -/- samples in at least half of the available probes. The direction of the fold change is only given when it exceeded 1.30. Fold changes lower than 1.30 were not considered significant.