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Table 5 Markers for macrophages/dendritic cells.

From: Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model

    Slc26a4 +/+ Slc26a4 -/-   
No. Gene Description Intensity P Intensity P Fold Direction
1 Ptprc Cd45 antigen 226 3/3 946 3/3 4.19 up
2 Cd83 Cd83 antigen 126 0/3 524 3/3 4.16 up
3 Cd68 Cd68 antigen 170 3/3 1,344 3/3 7.90 up
4 Cd14 Cd14 antigen 412 1/3 619 3/3 1.50 up
5 H2-Aa MHC class II 264 5/12 1,019 9/12 4.00 up
6 H2-Ab MHC class II 126 0/9 279 3/9 1.86 up
7 H2-Eb1 MHC class II 429 0/3 1,010 3/3 2.35 up
8 Lgals3 Mac2 antigen 91 2/6 1,866 5/6 13.49 up
9 Itgax Integrin alpha X 125 0/3 375 3/3 3.00 up
10 Emr1 Mucin receptor 750 3/3 1,547 3/3 2.06 up
11 Lyzs Lysozyme 551 6/9 8257 9/9 11.78 up
12 H2-K1 MHC class I (D-region) 1,607 13/18 4,062 15/18 2.06 up
13 H2-K1 MHC class I (K-region) 1,828 6/12 2,883 6/12 1.54 up
14 H2-K1 MHC class I (Q-region) 549 1/3 890 3/3 1.62 up
15 C1r Complement 37 2/6 266 6/6 13.87 up
16 C1s Complement 71 0/3 200 1/3   
17 C1qa Complement 355 1/3 2,905 3/3 8.19 up
18 C1qb Complement 552 5/6 2,001 6/6 4.43 up
19 C2 Complement 3,207 9/9 4,794 6/6 1.62 up
20 C3 Complement 11 0/3 231 2/3 20.68 up
21 C4 Complement 1,556 3/3 4,788 3/3 3.08 up
22 C3ar1 Complement receptor 177 3/9 482 6/9 2.93 up
23 Ctss Cathepsin S 2,304 3/3 7,394 3/3 3.21 up
24 Ctsk Cathepsin K 170 1/3 377 3/3 2.21 up
25 Ctsb Cathepsin B 4,172 12/15 6,576 12/15 1.90 up
26 Msr2 Macrophage scavenger receptor 169 3/3 1140 3/3 6.75 up
27 Mpeg1 Macrophage expressed gene 582 0/3 5,527 3/3 9.49 up
28 Cst3 Cystatin C 5,562 3/3 8,652 3/3 1.56 up
29 Fcgr1 IgG receptor, high affinity 98 0/6 163 5/6 1.70 up
30 Fcgr2b IgG receptor, low affinity 112 2/15 377 7/15 3.94 up
  1. Genes that can serve as markers macrophages/dendritic cells (1–10) and genes that are consistent with the presence of macrophages/dendritic cells (11–27) are listed. For parameters 'P', 'Fold' and 'Direction', see the Gene array section in Methods. Fold changes are given when a gene was called Present (P) in Slc26a4 +/- or Slc26a4 -/- samples in at least half of the available probes. The direction of the fold change is only given when it exceeded 1.30. Fold changes lower than 1.30 were not considered significant.