Skip to main content

Table 1 HLA-A, -B and -C carrier frequencies of stage IV melanoma patients. HLA-A and B alleles of 739 and 709 stage IV melanoma patients were typed serologically; HLA-C (391 stage IV melanoma patients) was typed by PCR. The frequencies of all alleles included in the analysis are shown. Subtypes are given in italics; the main types that have been partially subtyped are shown in bold. HLA carrier frequencies of the main types that have been partially subtyped encompass the carrier frequencies of the subtypes; the fraction of patients who have been subtyped for a certain allele is given as a percentage.

From: HLA-B8 association with late-stage melanoma – an immunological lesson?

HLA-A (n = 739) HLA-B (n = 709) HLA-C (n = 391)
serotype frequency subtyped serotype frequency subtyped allele frequency
HLA-A1 28.69%   HLA-B5 12.55% 89.89% HLA-Cw1 5.88%
HLA-A2 51.42%   HLA-B51 10.30%   HLA-Cw2 12.53%
HLA-A3 28.96%   HLA-B52 0.99%   HLA-Cw3 23.02%
HLA-A9 23.68% 99.43% HLA-B7 27.79%   HLA-Cw4 23.53%
HLA-A23 5.41%   HLA-B8 16.22%   HLA-Cw5 12.79%
HLA-A24 18.13%   HLA-B12 24.96% 98.31% HLA-Cw6 23.27%
HLA-A10 11.23% 98.80% HLA-B44 23.41%   HLA-Cw7 48.34%
HLA-A25 5.55%   HLA-B45 1.13%   HLA-Cw8 3.07%
HLA-A26 5.01%   HLA-B13 5.64%    
HLA-A34 0.14%   HLA-B14 4.80% 29.41%   
HLA-A66 0.41%   HLA-B64 0.28%    
HLA-A11 9.34%   HLA-B65 1.13%    
HLA-A19 22.46% 96.99% HLA-B15 14.10% 79.00%   
HLA-A29 5.82%   HLA-B62 10.58%    
HLA-A30 2.98%   HLA-B63 0.56%    
HLA-A31 5.14%   HLA-B75 0.00%    
HLA-A32 5.55%   HLA-B16 9.59% 98.53%   
HLA-A33 2.30%   HLA-B38 4.94%    
HLA-A28 6.63% 36.73% HLA-B39 4.51%    
HLA-A68 2.03%   HLA-B18 10.58%    
HLA-A69 0.41%   HLA-B21 4.65% 96.97%   
    HLA-B49 2.26%    
    HLA-B50 2.26%    
    HLA-B22 3.24% 95.65%   
    HLA-B54 0.14%    
    HLA-B55 1.41%    
    HLA-B56 1.55%    
    HLA-B27 8.89%    
    HLA-B35 15.23%    
    HLA-B37 3.95%    
    HLA-B40 11.99% 90.59%   
    HLA-B60 8.46%    
    HLA-B61 2.40%    
    HLA-B41 2.96%