Table 1 HLA-A, -B and -C carrier frequencies of stage IV melanoma patients. HLA-A and B alleles of 739 and 709 stage IV melanoma patients were typed serologically; HLA-C (391 stage IV melanoma patients) was typed by PCR. The frequencies of all alleles included in the analysis are shown. Subtypes are given in italics; the main types that have been partially subtyped are shown in bold. HLA carrier frequencies of the main types that have been partially subtyped encompass the carrier frequencies of the subtypes; the fraction of patients who have been subtyped for a certain allele is given as a percentage.
From: HLA-B8 association with late-stage melanoma – an immunological lesson?
HLA-A (n = 739) | HLA-B (n = 709) | HLA-C (n = 391) | |||||
|---|---|---|---|---|---|---|---|
serotype | frequency | subtyped | serotype | frequency | subtyped | allele | frequency |
HLA-A1 | 28.69% | HLA-B5 | 12.55% | 89.89% | HLA-Cw1 | 5.88% | |
HLA-A2 | 51.42% | HLA-B51 | 10.30% | HLA-Cw2 | 12.53% | ||
HLA-A3 | 28.96% | HLA-B52 | 0.99% | HLA-Cw3 | 23.02% | ||
HLA-A9 | 23.68% | 99.43% | HLA-B7 | 27.79% | HLA-Cw4 | 23.53% | |
HLA-A23 | 5.41% | HLA-B8 | 16.22% | HLA-Cw5 | 12.79% | ||
HLA-A24 | 18.13% | HLA-B12 | 24.96% | 98.31% | HLA-Cw6 | 23.27% | |
HLA-A10 | 11.23% | 98.80% | HLA-B44 | 23.41% | HLA-Cw7 | 48.34% | |
HLA-A25 | 5.55% | HLA-B45 | 1.13% | HLA-Cw8 | 3.07% | ||
HLA-A26 | 5.01% | HLA-B13 | 5.64% | ||||
HLA-A34 | 0.14% | HLA-B14 | 4.80% | 29.41% | |||
HLA-A66 | 0.41% | HLA-B64 | 0.28% | ||||
HLA-A11 | 9.34% | HLA-B65 | 1.13% | ||||
HLA-A19 | 22.46% | 96.99% | HLA-B15 | 14.10% | 79.00% | ||
HLA-A29 | 5.82% | HLA-B62 | 10.58% | ||||
HLA-A30 | 2.98% | HLA-B63 | 0.56% | ||||
HLA-A31 | 5.14% | HLA-B75 | 0.00% | ||||
HLA-A32 | 5.55% | HLA-B16 | 9.59% | 98.53% | |||
HLA-A33 | 2.30% | HLA-B38 | 4.94% | ||||
HLA-A28 | 6.63% | 36.73% | HLA-B39 | 4.51% | |||
HLA-A68 | 2.03% | HLA-B18 | 10.58% | ||||
HLA-A69 | 0.41% | HLA-B21 | 4.65% | 96.97% | |||
HLA-B49 | 2.26% | ||||||
HLA-B50 | 2.26% | ||||||
HLA-B22 | 3.24% | 95.65% | |||||
HLA-B54 | 0.14% | ||||||
HLA-B55 | 1.41% | ||||||
HLA-B56 | 1.55% | ||||||
HLA-B27 | 8.89% | ||||||
HLA-B35 | 15.23% | ||||||
HLA-B37 | 3.95% | ||||||
HLA-B40 | 11.99% | 90.59% | |||||
HLA-B60 | 8.46% | ||||||
HLA-B61 | 2.40% | ||||||
HLA-B41 | 2.96% | ||||||