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Table 2 Serum alanine aminotransferase (ALT) measures (intent to treat analysis)

From: The effect of acetaminophen (four grams a day for three consecutive days) on hepatic tests in alcoholic patients – a multicenter randomized study

  Serum ALT (IU/L)
  Acetaminophen group Placebo Group p-value*
Day 0:    
Mean ± SD 49 ± 38 47 ± 37 0.398
Range 4–189 8–175  
n 308 135  
Day 2:    
Mean ± SD 45 ± 38 46 ± 34 0.949
Range 7–292 6–174  
n 287 124  
Day 3:    
Mean ± SD 45 ± 36 50 ± 38 0.245
Range 7–230 6–242  
n 274 118  
Day 4:    
Mean ± SD 48 ± 39 52 ± 43 0.411
Range 6–264 8–288  
n 267 115  
Day 5:    
Mean ± SD 57 ± 45 55 ± 48 0.706
Range 7–312 7–282  
n 261 114  
  1. *Standardized values based upon upper limit of normal were used to calculate p-values.
  2. Normal ranges for CARES: ALT 5–40 IU/L male and 5–36 IU/L female. Two different labs were used by RCKC, normal ranges: ALT 0–50 IU/L and 2–60 IU/L male, 2–40 IU/L female.