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Table 1 Two-way interactions detected by the three methods with a P-value less than 5%

From: Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario

Rank LRM CART MDR
  Interaction P-value Interaction P-value Interaction P-value
1 XPD-[Lys751Gln]
IL10-[G(-1082)A]
0.013 XPD-[Lys751Gln]
IL10-[G(-1082)A]
0.006* XPD-[Lys751Gln]
IL10-[G(-1082)A]
0.009*
2 COMT-[Met108/158Val]
CCND1-[Pro241Pro]
0.020 CYP17-[C(518)T]
BARD1-[Pro24Ser]
0.013 COMT-[Met108/158Val]
CCND1-[Pro241Pro]
0.019
3 TNFA-[G(-308)A]
p27-[Val109Gly]
0.046    BARD1-[Pro24Ser]
XPD-[Lys751Gln]
0.037
4      IL13-[Arg130Gln]
CYP17-[C(518)T]
0.037
  1. *Significant after Bonferroni correction for the number of tests performed in the second stage analysis.