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Table 2 Interactions and risk subgroups identified by CART with a P-value less than 5%

From: Methodological issues in detecting gene-gene interactions in breast cancer susceptibility: a population-based study in Ontario

Rank Interaction P-value
1 XPD-[Lys751Gln]
IL10-[G(-1082)A]
0.006
2 CYP17-[C(518)T]
BARD1-[Pro24Ser]
0.013
3 XPD-[Lys751Gln]
IL10-[G(-1082)A]
IL1A-[Ala114Ser]
ESR1-[Ser10Ser]
0.016
4 CYP17-[C(518)T]
IL13-[Arg130Gln]
IL1A-[Ala114Ser]
MTHFR-[Ala222Val]
PTEN-[(IVS4+109)ins/del5
0.019
5 XPD-[Lys751Gln]
BARD1-[Pro24Ser]
MTHFR-[Ala222Val]
0.020
6 CYP17-[C(518)T]
BARD1-[Pro24Ser]
MTHFR-[Ala222Val]
0.043
7 XPD-[Lys751Gln]
GADD45-[C(IVS3+168)T]
GSTP1-[Ile105Val]
0.050