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Table 3 Comparison of cluster 1 and cluster 2 studies (mean ± SD)

From: A meta-analysis of N-acetylcysteine in contrast-induced nephrotoxicity: unsupervised clustering to resolve heterogeneity

  Characteristic Cluster 1 Cluster 2 p-value
Study-related Publication date (months after first) 38 ± 8 22 ± 17 0.05
  Study size (number of patients) 136 ± 106 75 ± 35 0.23
  Jadad score (1–5) 2.9 ± 1.5 2.0 ± 1.4 0.24
  All three factors combined 34 ± 13 50 ± 9 0.01
Patient-related Age (years) 68 ± 4 70 ± 3 0.24
  Baseline creatinine (mg/dl) 1.6 ± 0.4 2.2 ± 0.6 0.09
  Diabetes mellitus (%) 43 ± 13 45 ± 13 0.93
  Female (%) 31 ± 14 22 ± 9 0.31
  Contrast volume (ml) 158 ± 61 122 ± 46 0.11
  1. † Wilcoxon rank sum test