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Table 1 Differentially expressed microRNAs in anaplastic astrocytoma and/or glioblastoma multiforme tumors relative to non-neoplastic brain tissue

From: miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

Glioblastoma multiforme and anaplastic astrocytoma Glioblastoma multiforme only Anaplastic astrocytoma only
  Fold change glioblastoma multiforme Fold change anaplastic astrocytoma Ref   Fold change glioblastoma multiforme Ref   Fold change anaplastic astrocytoma Ref
Down-regulated     Down-regulated    Down-regulated   
miR-7 34 13   miR-101 4   miR-125b 153 [22]
miR-31 17 9   miR-128a 27 [22] miR-126 7  
miR-107 14 10   miR-132 7   miR-127 149  
miR-124 57 26   miR-133a 17   miR-134 9  
miR-124b 45 27   miR-133b 14     
miR-129 43 27   miR-149 9   Up-regulated   
miR-137 63 66   miR-153 12   miR-296 11  
miR-138 27 12 [21] miR-154* 7   miR-320 5  
miR-139 66 34   miR-185 5     
miR-187 6 5   miR-29b 6     
miR-203 13 4   miR-323 17     
miR-218 40 16   miR-328 8     
     miR-330 18     
Up-regulated          
miR-10b 35 75 [22] Up-regulated      
     miR-21 7 [21, 22]    
     miR-155 8     
     miR-210 7     
  1. P-values for all miRNAs are P < 0.05 for comparisons of miRNA expression in tumors versus glioses; for miRNAs in bold P < 0.01. References indicate high-grade astrocytoma miRNA expression studies in which miRNA has been described previously.
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BMC Medicine

ISSN: 1741-7015

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