Table 4 Reduction in biopsies/cancers detected, as compared with the current study, using as a threshold for biopsy a 20% or higher probability of cancer
Number of biopsies | Number of cancers | Number of high-grade cancers | ||||
|---|---|---|---|---|---|---|
Performed | Reduced (%) | Caught | Missed (%) | Caught | Missed (%) | |
Biopsy all | 740 | n/a | 192 | n/a | 40 | n/a |
Laboratory model | ||||||
Base | 489 | 251 (34%) | 153 | 39 (20%) | 38 | 2 (5%) |
Base+free PSA | 380 | 360 (49%) | 152 | 40 (21%) | 36 | 4 (10%) |
Full | 316 | 424 (57%) | 161 | 31 (16%) | 37 | 3 (8%) |
Clinical model | ||||||
Base | 344 | 396 (54%) | 136 | 56 (29%) | 37 | 3 (8%) |
Base+free PSA | 336 | 404 (55%) | 147 | 45 (23%) | 38 | 2 (5%) |
Full | 297 | 443 (60%) | 159 | 33 (17%) | 39 | 1 (3%) |