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Figure 1 | BMC Medicine

Figure 1

From: Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia

Figure 1

Age-related changes in hemoglobin concentration, red cell CR1, CD55, and IC binding capacity. For multiple comparison testing all groups were compared with the group formed by collapsing the groups ranging in age from >6 to ≤ 36 months (bracket). P values were adjusted using the Sidak correction for multiple comparisons. * = 0.01 <P ≤ 0.05, ** = P < 0.01. a. Hemoglobin level. Unadjusted ANOVA for differences across groups P = 9.6 × 10-38. After adjustment for red cell CR1, red cell CD55, %C3b-positive red cells, malaria status, and parasite density, significant differences were found as indicated. b. Red cell CR1. Unadjusted ANOVA for differences across groups P = 1.5 × 10-10. After adjustment for malaria status and parasite density differences were found as indicated. c. Red cell CD55. Unadjusted ANOVA for differences across groups P = 6.1 × 10-6. After adjustment for malaria status and parasite density significant differences were found as indicated. ABC = Antibody binding capacity. d. binding capacity. Unadjusted ANOVA for differences across groups P = 0.004. After adjustment for malaria status and parasite density significant differences were found as indicated.

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