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Table 3 Univariate analysis of variance for %C3b-positive red cells as dependent variable

From: Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia

  

Unadjusted

Adjusted

Groups

Independent Variables

F

B (SE)

95% CI of B

η 2 p

P

F

B (SE)

95% CI of B

η 2 p

P

All

Age Groups (months)

21.8

--

--

0.245

5.9 × 10-19

11.6

--

--

0.149

2.5 × 10-10

N = 342

0 to ≤ 6

--

4.13 (2.53)

-0.85 to 9.10

0.008

0.10

--

3.29 (2.45)

-1.38 to 8.29

0.006

0.18

 

>6 to ≤ 36

--

15.08 (1.75)

11.63 to 18.53

0.180

3.1 × 10-16

--

11.61 (1.81)

8.05 to 15.18

0.111

1.8 × 10-10

 

>36 to ≤ 72

--

9.17 (2.28)

4.68 to 13.66

0.046

7.3 × 10-5

--

5.99 (2.30)

1.48 to 10.51

0.020

0.01

 

>72 to ≤ 144

--

7.64 (2.33)

3.05 to 12.23

0.031

1.2 × 10-3

--

4.61 (2.36)

-0.03 to 9.24

0.011

0.07

 

>144 to ≤ 288

--

-1.64 (2.72)

-7.00 to 3.72

0.001

0.55

--

-1.38 (2.68)

-6.64 to 3.88

0.001

0.54

 

>288 to ≤ 540*

--

--

--

--

--

--

--

--

--

--

 

CR1

46.1

-0.026 (0.004)

-0.034 to -0.019

0.119

5.1 × 10-11

3.2

-0.008 (0.004)

-0.016 to 0.001

0.010

0.07

 

CD55

35.3

-0.007 (0.001)

-0.009 to -0.004

0.094

7.0 × 10-9

5.5

-0.003 (0.001)

-4.8 × 10-3 to -0.4 × 10-3

0.016

0.02

 

Malaria Negative†

17.8

-5.7 (1.4)

-8.4 to -3.1

0.050

3.2 × 10-5

6.4

-3.34 (1.32)

-5.93 to -0.74

0.019

0.01

 

Parasite Density

8.8

1.9 × 10-4 (0.6 × 10-4)

0.6 × 10-4 to 3.2 × 10-4

0.025

3.2 × 10-3

0.5

4.1 × 10-5 (5.9 × 10-5)

-0.8 × 10-4 to 1.6 × 10-4

0.001

0.49

 

ICBC

12.9

-0.358 (0.100)

-0.554 to -0.162

0.037

3.8 × 10-4

2.0

-0.130 (0.092)

-0.311 to 0.050

0.006

0.16

Malaria-treated

Age Groups (months)

12.7

--

--

0.306

3.2 × 10-10

9.0

--

--

0.244

1.8 × 10-7

N = 150

0 to ≤ 6

--

12.36 (6.06)

0.38 to 24.35

0.028

0.04

--

10.08 (6.38)

-2.53 to 22.68

0.018

0.12

 

>6 to ≤ 36

--

21.48 (3.88)

13.81 to 29.15

0.175

1.4 × 10-7

--

20.00 (4.13)

11.83 to 28.18

0.143

3.4 × 10-6

 

>36 to ≤ 72

--

10.68 (4.28)

2.23 to 19.13

0.042

0.01

--

10.01 (4.42)

1.28 to 18.73

0.035

0.03

 

>72 to ≤ 144

--

9.49 (4.28)

1.04 to 17.94

0.033

0.02

--

8.25 (4.43)

-0.51 to 17.00

0.024

0.07

 

>144 to ≤ 288

--

-0.78 (5.22)

-11.11 to 9.53

1.6 × 10-4

0.88

--

-0.69 (5.26)

-11.10 to 9.72

1.2 × 10-4

0.90

 

>288 to ≤ 540*

--

--

--

 

--

--

--

--

--

--

 

CR1

13.7

-0.030 (0.008)

-0.046 to -0.014

0.085

3.0 × 10-4

3.0

-0.015 (0.009)

-.032 to 0.002

0.021

0.09

 

CD55

7.2

-0.005 (0.002)

-0.009 to -0.001

0.047

7.9 × 10-3

0.01

2.5 × 10-4 (21.1 × 10-4)

-0.004 to 0.004

1.0 × 10-4

0.91

 

Parasite Density

2.6

1.2 × 10-4 (0.8 × 10-4)

-0.3 × 10-4 to 2.7 × 10-4

0.017

0.11

0.1

-1.9 × 10-5 (6.8 × 10-5)

-1.5 × 10-4 to 1.1 × 10-4

0.001

0.78

 

ICBC

0.2

-0.069 (0.171)

-0.408 to 0.269

0.001

0.69

0.3

0.085 (0.155)

-0.222 to 0.392

0.002

0.59

Malaria Negative

Age Groups (months)

9.9

--

--

0.210

2.2 × 10-8

4.8

--

--

0.116

6.3 × 10-5

N = 192

0 to ≤ 6

--

2.07 (2.50)

-2.87 to 7.00

0.004

0.41

--

1.76 (2.35)

-2.93 to 6.34

0.003

0.47

 

>6 to ≤ 36

--

10.80 (1.84)

7.17 to 14.43

0.156

2.0 × 10-8

--

7.93 (1.82)

4.71 to 11.78

0.094

7.9 × 10-6

 

>36 to ≤ 72

--

9.23 (2.95)

3.41 to 15.06

0.050

0.002

--

7.76 (2.78)

2.49 to 13.43

0.041

4.6 × 10-3

 

>72 to ≤ 144

--

7.09 (3.21)

0.75 to 13.43

0.025

0.03

--

4.66 (3.05)

-1.44 to 10.60

0.013

0.13

 

>144 to ≤ 288

--

-1.42 (3.03)

-7.39 to 4.56

0.001

0.64

--

0.33 (2.91)

-5.83 to 5.45

7.0 × 10-5

0.95

 

>288 to ≤ 540*

--

--

--

--

--

--

--

--

--

--

 

CR1

29.4

-0.022 (0.004)

-0.030 to -0.014

0.134

1.8 × 10-7

1.0

-0.004 (0.005)

-0.014 to 0.005

0.005

0.33

 

CD55

27.0

-0.006 (0.001)

-0.009 to -0.004

0.124

5.2 × 10-7

8.6

-0.004 (0.001)

-0.006 to -0.001

0.045

3.8 × 10-3

 

ICBC

26.9

-0.564 (0.109)

-0.779 to -0.350

0.124

5.4 × 10-7

9.0

-0.326 (0.109)

-0.540 to -0.111

0.047

3.1 × 10-3

  1. *B for this group set to '0' as reference.
  2. † B for malaria-treated group was set to '0' as reference.
  3. η 2 p = Partial Eta squared or coefficient of non-linear correlation.
  4. ICBC = IC binding capacity.