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Table 4 Univariate analysis of variance for hemoglobin as dependent variable

From: Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia

   Unadjusted Adjusted
Groups Independent Variables F B (SE) 95% CI of B η 2 p P F B (SE) 95% CI of B η 2 p P
All Age Groups (months) 48.5 -- -- 0.419 9.6 × 10-38 26.5 -- -- 0.287 1.5 × 10-22
N = 342 0 to ≤ 6 -- -1.94 (0.36) -2.64 to -1.23 0.080 1.2 × 10-7 -- -1.86 (0.34) -2.54 to -1.18 0.080 1.5 × 10-7
  >6 to ≤ 36 -- -3.13 (0.25) -3.62 to -2.64 0.321 4.7 × 10-30 -- -2.59 (0.27) -3.13 to -2.07 0.219 7.3 × 10-19
  >36 to ≤ 72 -- -1.94 (0.32) -2.58 to -1.31 0.097 5.0 × 10-9 -- -1.72 (0.33) -2.36 to -1.08 0.078 2.3 × 10-7
  >72 to ≤ 144 -- -0.54 (0.33) -1.19 to 0.11 0.008 0.10 -- -0.35 (0.33) -1.01 to 0.30 0.003 0.29
  >144 to ≤ 288 -- 0.20 (0.39) -0.55 to 0.96 0.001 0.60 -- -0.11 (0.38) -0.85 to 0.63 2.6 × 10-4 0.77
  >288 to ≤ 540* -- -- -- -- -- -- -- -- -- --
  CR1 63.3 0.005 (0.001) 0.004 to 0.006 0.157 2.7 × 10-14 20.4 0.003 (0.001) 0.002 to 0.004 0.058 8.7 × 10-6
  CD55 10.3 5.9 × 10-4 (1.8 × 10-4) 2.3 × 10-4 to 9.5 × 10-4 0.029 1.5 × 10-3 5.9 -3.8 × 10-4 (1.6 × 10-4) -6.9 × 10-4 to -0.7 × 10-4 0.018 0.02
  Malaria Status 1.2 0.246 (0.224) -0.195 to 0.686 0.004 0.27 0.3 -0.103 (0.187) -0.471 to 0.265 0.001 0.58
  Parasite Density 4.9 -2.3 × 10-5 (1.0 × 10-5) -4.3 × 10-5 to -0.3 × 10-5 0.014 0.03 1.1 × 10-5 0.3 × 10-7 (82.7 × 10-7) -1.6 × 10-5 to 1.6 × 10-5 3.5 × 10-8 1.00
  ICBC 11.9 0.056 (0.016) 0.024 to 0.087 0.034 6.3 × 10-4 0.02 0.002 (0.013) -0.024 to 0.027 6.0 × 10-5 0.89
  %C3b-positive Red Cells 77.6 -0.070 (0.008) -0.085 to -0.054 0.186 6.6 × 10-17 10.5 -0.025 (0.008) -0.040 to -0.010 0.031 1.3 × 10-3
Malaria-treated Age Groups(months) 27.2 -- -- 0.486 2.7 × 10-19 15.3 -- -- 0.355 6.0 × 10-12
N = 150 0 to ≤ 6 -- -3.09 (0.68) -4.42 to -1.75 0.127 1.1 × 10-5 -- -2.74 (0.68) -4.09 to -1.39 0.103 1.0 × 10-4
  >6 to ≤ 36 -- -2.98 (0.43) -3.83 to -2.12 0.247 1.7 × 10-10 -- -2.54 (0.48) -3.48 to -1.60 0.170 3.7 × 10-7
  >36 to ≤ 72 -- -1.53 (0.48) -2.47 to -0.59 0.067 1.7 × 10-3 -- -1.45 (0.48) -2.39 to -0.50 0.062 2.9 × 10-3
  >72 to ≤ 144 -- -0.12 (0.48) -1.06 to 0.82 4.5 × 10-4 0.80 -- -0.03 (0.48) -0.91 to 0.97 3.0 × 10-5 0.95
  >144 to ≤ 288 -- -0.31 (0.58) -1.46 to 0.85 0.002 0.60 -- -0.46 (0.56) -1.56 to 0.65 0.005 0.41
  >288 to ≤ 540* -- -- --   -- -- -- -- -- --
  CR1 28.2 0.005 (0.001) 0.003 to 0.007 0.160 3.9 × 10-7 13.0 0.003 (0.001) 0.002 to 0.005 0.085 4.4 × 10-4
  CD55 7.2 7.0 × 10-4 (2.6 × 10-4) 1.9 × 10-4 to 12.2 × 10-4 0.047 8.1 × 10-3 2.0 -3.2 × 10-4 (2.2 × 10-4) -7.6 × 10-4 to 1.3 × 10-4 0.014 0.16
  Parasite Density 5.0 -2.2 × 10-5 (1.0 × 10-5) -4.1 × 10-5 to -0.3 × 10-5 0.033 0.03 0.002 3.2 × 10-7 (0.7 × 10-7) -1.4 × 10-5 to 1.5 × 10-5 1.4 × 10-5 0.96
  ICBC 3.2 0.039 (0.022) 0.004 to 0.083 0.021 0.08 0.3 0.008 (0.017) -0.024 to 0.041 0.002 0.61
  %C3b-positive Red Cells 34.9 -0.057 (0.010) -0.075 to -0.038 0.191 2.3 × 10-8 1.9 -0.012 (0.009) -0.030 to 0.005 0.014 0.17
Malaria Negative Age Groups (months) 26.4 -- -- 0.415 4.4 × 10-20 14.4 -- -- 0.284 7.0 × 10-12
N = 192 0 to ≤ 6 -- -1.65 (0.44) -2.51 to -0.79 0.072 2.1 × 10-4 -- -1.63 (0.42) -2.46 to -0.80 0.077 1.4 × 10-4
  >6 to ≤ 36 -- -3.15 (0.32) -3.78 to -2.52 0.342 1.2 × 10-18 -- -2.62 (0.34) -3.30 to -1.95 0.246 8.0 × 10-13
  >36 to ≤ 72 -- -2.41 (0.51) -3.43 to -1.40 0.106 5.2 × 10-6 -- -1.97 (0.51) -2.97 to -0.97 0.077 1.4 × 10-4
  >72 to ≤ 144 -- -1.15 (0.56) -2.25 to -0.04 0.022 0.04 -- -0.98 (0.55) -2.06 to 0.10 0.017 0.07
  >144 to ≤ 288 -- 0.65 (0.53) -0.39 to 1.69 0.008 0.22 -- 0.31 (0.52) -0.71 to 1.33 0.002 0.55
  >288 to ≤ 540* -- -- -- -- -- -- -- -- -- --
  CR1 33.9 0.005 (0.001) 0.003 to 0.006 0.151 2.4 × 10-8 7.6 0.002 (0.001) 0.001 to 0.004 0.040 0.01
  CD55 3.5 4.9 × 10-4 (2.6 × 10-4) -0.2 × 10-4 to 10.0 × 10-4 0.018 0.06 5.0 -4.9 × 10-4 (2.2 × 10-4) -9.3 × 10-4 to -0.6 × 10-4 0.027 0.03
  ICBC 8.6 0.068 (0.023) 0.022 to 0.113 0.043 3.7 × 10-3 0.4 -0.012 (0.020) -0.052 to 0.027 0.002 0.53
  %C3b-positive Red Cells 46.3 -0.090 (0.013) -0.116 to -0.064 0.196 1.3 × 10-10 10.7 -0.043 (0.013) -0.069 to -0.017 0.056 1.3 × 10-3
  1. *B for this group set to '0' as reference.
  2. B for malaria-treated group was set to '0' as reference.
  3. η 2 p = Partial Eta squared or coefficient of non-linear correlation.
  4. ICBC = IC binding capacity.