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Table 4 Top SNPs ranked by univariate analysis for trial E9486.

From: Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival

Rank rs ID pval Gene Sym Gene Name SNP Function
1.0 rs10018625 0.001536 TAG ERROR TAG ERROR unknown, TAG ERROR
2.0 rs1047643 0.001603 FDFT1 Farnesyl-diphosphate farnesyltransferase 1 coding-synon
3.0 rs20541 0.001644 IL13 Interleukin 13 coding-nonsynon
4.0 rs2108622 0.0020374 CYP4F2 Cytochrom P450, family 4, subfamily F, polypeptide 2 coding-nonsynon
5.0 rs3759259 0.002362 STYK1 Protein kinase STYK1 coding-nonsynon
6.0 rs1801133 0.003251 MTHFR 5, 10-methylenetetrahydrofolate reductase (NADPH) coding-nonsynon
7.0 rs2069456 0.003375 CDK5 Cyclin-dependent kinase 5 intron
8.0 rs1131532 0.005650 TNFSF10 Tumor necrosis factor (ligand) superfamily, member 10 coding-synon
9.0 rs882709 0.005965 SETX senataxin coding-nonsynon
10.0 rs4646421 0.007847 CYP1A1 Cytochrome P450, family 1, subfamily A, polypeptide 1 intron
11.0 rs1799969 0.008221 ICAM1 Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor coding-nonsynon
12.0 rs3822430 0.009157 SRD5A1 Steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) coding-synon
13.0 rs7903344 0.009471 CHUK Conserved helix-loop-helix ubiquitous kinase coding-nonsynon
14.0 rs13926 0.011531 TRAP1 TNF receptor-associated protein 1 coding-nonsynon
15.0 rs3172469 0.012006 BCL6 B-cell CCL/lymphoma 6 (zinc finger protein 51) intron
16.0 rs215101 0.012028 ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 intron, TagSNP:ABCC1
17.0 rs2227564 0.012246 PLAU Plasminogen activator, urokinase coding-nonsynon
18.0 rs3096057 0.012484 CSF1 Colony stimulating factor 1 (macrophage) Promoter
19.0 rs6474491 0.013935 STAR Steriodogenic acute regulator Promoter
20.0 rs2066471 0.015231 MTHRF 5, 10-methlyenetetrahydrofolate reductase (NADPH) intron