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Table 1 Comparison of patients included in two placebo-controlled trials of antibiotics in acute exacerbation of chronic bronchitis

From: The problems of meta-analysis for antibiotic treatment of chronic obstructive pulmonary disease, a heterogeneous disease: a commentary on Puhan et al

Characteristic Anthonisen Sachs
N 362 71
Age in years (mean ± standard deviation) 67.3 ± 9 51.7 ± 16.3
Minimum age for inclusion in years 35 18
Smoking in pack-years (mean ± standard deviation) 39.9 ± 28.9 16.5 (0.15–77)
Smokers (% of subjects) 93.6 69.1
Asthmatics Excluded Included
Forced expiratory volume1 (% predicted) 33.9 ± 3.7 NA
Peak expiratory flow (liter/minute) 227.5 ± 96.1 285.3 ± 99.2
  1. Data from Anthonisen et al [4] and Sachs et al [5].