Table 1 Comparison of patients included in two placebo-controlled trials of antibiotics in acute exacerbation of chronic bronchitis
Characteristic | Anthonisen | Sachs |
|---|---|---|
N | 362 | 71 |
Age in years (mean ± standard deviation) | 67.3 ± 9 | 51.7 ± 16.3 |
Minimum age for inclusion in years | 35 | 18 |
Smoking in pack-years (mean ± standard deviation) | 39.9 ± 28.9 | 16.5 (0.15–77) |
Smokers (% of subjects) | 93.6 | 69.1 |
Asthmatics | Excluded | Included |
Forced expiratory volume1 (% predicted) | 33.9 ± 3.7 | NA |
Peak expiratory flow (liter/minute) | 227.5 ± 96.1 | 285.3 ± 99.2 |