Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study

Table 2 The age and sex adjusted and multivariate adjusted association of the SNPs with incident CHD and MI

		Allele	All participants	Incident cases	Age and sex adjusted	Multivariate adjusted HR*
CHD	rs10757274	G	45.8	45.5	1.03 (0.90, 1.18)	1.00 (0.87, 1.15)
	rs10757278	G	44.9	42.7	1.03 (0.90, 1.18)	1.00 (0.87, 1.15)
MI	rs10757274	G	45.8	43.8	0.94 (0.82, 1.08)	0.97 (0.84, 1.11)
	rs10757278	G	44.9	42.7	0.93 (0.81, 1.06)	0.95 (0.83, 1.10)

* adjusted for age, sex, BMI, serum total and HDL cholesterol, smoking, diabetes, systolic and diastolic blood pressure.
CI = Confidence interval, CHD = Coronary heart disease, MI = Myocardial infarction

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