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Table 3 Mean onset ages stratified by LRRK2 mutations and sex are shown

From: The Gly2019Ser mutation in LRRK2is not fully penetrant in familial Parkinson's disease: the GenePD study

  G2019S R1441C No LRRK2 mutations
  Men Women Men Women Men Women
No. of cases (%) 32 (53.3%) 28 (46.7%) 1 (25%) 3 (75%) 549 (56.9%) 416 (43.1%)
Mean onset age 60.0 59.9 53.0 67.0 60.0 59.7
No. of familial cases (%) 29 (53.7%) 25 (46.3%) 1 (25%) 3 (75%) 471 (55.7%) 374 (44.3%)
Mean onset age 59.9 59.3 53.0 67.0 60.9 59.9
No. of idiopathic cases (%) 3 (50%) 3 (50%) 0 0 78 (65.0%) 42 (35.0%)
Mean onset age 61.0 64.3 - - 55.0 57.7
  1. No significant differences in onset age were detected in any category.