Name | Fold change C99WT/mock |
P-value |
---|
| Transcriptomics | Proteomics | Transcriptomics | Proteomics |
---|
CRABP1
|
1.0
|
1.4
|
0.979
|
0.042
|
NEF3 | -3.4 | -1.8 | 0.024 | 0.086 |
NEFL | -3.0 | -1.3 | 0.039 | 0.11 |
INA | -1.9 | -1.3 | 0.069 | 0.029 |
- Comparison between C99WT and mock-transfected cells revealed effects mediated by C99. Neurofilament 3 (NEF3), neurofilament light polypeptide 68 kDa (NEFL) and internexin neuronal intermediate filament protein alpha (INA) were down-regulated as a consequence of C99-overexpression. CRABP1 was not differentially expressed (cut-off for differential expression at least 1.9 on the transcript or protein level, respectively).