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Table 2 Real-time quantitative PCR analysis.

From: Different atrophy-hypertrophy transcription pathways in muscles affected by severe and mild spinal muscular atrophy

  SMA I SMA III
Gene Expression value Expression value
IGF-1R +3.2 -2.9
FRAP1
(MTOR)
1 +2.8
FOXO3A +1.3 -1.6
eIF4EBP1 -1.4 -1.7
FBOX32
(Atrogin-1)
-1.6 -1.7
TRAF2 1 +4.2
MAPK14
(p38)
-1.25 +1.6
RRAS2 -2 -2.5
MAPK1
(ERK)
+1.2 +2.4
  1. Expression ratios of selected intracellular signaling molecules of atrophy and hypertrophy pathways tested in affected SMAI and III muscles versus control muscles (p < 0.05).