Table 1 Frequency of clinical features in cases and controls.
Cases (N= 5477) | Controls (N= 38,314) | Positive likelihood ratio (95% CI) | |||
|---|---|---|---|---|---|
Clinical feature | Number with this feature | Percentage with this feature | Number with this feature | Percentage with this feature | |
Symptoms | |||||
Constipation | 1477 | 27.0 | 4051 | 10.6 | 2.6 (2.4 to 2.7) |
Diarrhoea | 988 | 18.0 | 2171 | 5.7 | 3.2 (3.0 to 3.4) |
Change in bowel habit | 615 | 11.2 | 375 | 1.0 | 5.5 (5.2 to 5.8) |
Rectal bleeding | 853 | 15.6 | 460 | 1.2 | 6.0 (5.7 to 6.3) |
Weight loss | |||||
5.0–9.9% | 210 | 3.8 | 852 | 2.2 | 1.6 (1.4 to 1.8) |
≥ 10% | 351 | 6.4 | 678 | 1.8 | 2.9 (2.6 to 3.1) |
Abdominal pain | 1629 | 29.7 | 3121 | 8.1 | 3.5 (3.3 to 3.7) |
Investigations | |||||
Haemoglobin < 12.0 g/dl | 1424 | 26.0 | 1803 | 4.7 | 4.4 (4.2 to 4.6) |
Mean red cell volume < 80 fl | 363 | 6.6 | 923 | 2.4 | 2.8 (2.4 to 3.1) |
Diagnoses and risk factors | |||||
Irritable bowel syndrome | 135 | 2.5 | 325 | 0.8 | 2.4 (2.1 to 2.8) |
Diabetes | 626 | 11.4 | 3679 | 9.6 | 1.2 (1.1 to 1.3) |
Obesity | 510 | 9.3 | 3510 | 9.2 | 1.0 (0.93 to 1.1) |