Table 4 Diagnostic accuracy of the pediatric non-alcoholic fatty liver disease fibrosis index.
Cut-point | n | % | TPR | TNR | PLR | NLR | PPV | NPV |
|---|---|---|---|---|---|---|---|---|
≥ 1 | 198 | 97.5 | 99.3 (96.1 to 100.0) | 6.4 (1.8 to 15.7) | 1.1 (1.0 to 1.1) | 0.1 (0.01 to 1.0) | 70.7 (63.8 to 76.9) | 80.0 (28.4 to 99.5) |
≥ 2 | 190 | 93.6 | 97.2 (92.9 to 99.2) | 14.5 (6.9 to 25.8) | 1.1 (1.0 to 1.3) | 0.2 (0.1 to 0.6) | 72.1 (65.2 to 78.4) | 69.2 (38.6 to 90.9) |
≥ 3 | 179 | 88.2 | 95.7 (91.0 to 98.4) | 29.0 (18.2 to 41.9) | 1.3 (1.1 to 1.6) | 0.2 (0.1 to 0.3) | 75.4 (68.4 to 81.5) | 75.0 (53.3 to 90.2) |
≥ 4 | 167 | 82.3 | 93.6 (88.2 to 97.0) | 43.5 (31.0 to 56.7) | 1.7 (1.3 to 2.1) | 0.2 (0.1 to 0.3) | 79.0 (72.1 to 84.9) | 75.0 (57.8 to 87.9) |
≥ 5 | 154 | 75.9 | 88.7 (82.2 to 93.4) | 53.2 (40.1 to 66.0) | 1.9 (1.4 to 2.5) | 0.2 (0.1 to 0.4) | 81.2 (74.1 to 87.0) | 67.3 (52.5 to 80.1) |
≥ 6 | 138 | 68.0 | 81.6 (74.2 to 87.6) | 62.9 (49.7 to 74.8) | 2.2 (1.6 to 3.1) | 0.3 (0.2 to 0.4) | 83.3 (76.0 to 89.1) | 60.0 (47.1 to 72.0) |
≥ 7 | 118 | 58.1 | 76.6 (68.7 to 83.3) | 83.9 (72.3 to 92.0) | 4.7 (2.7 to 8.4) | 0.3 (0.2 to 0.4) | 91.5 (85.0 to 95.9) | 61.2 (50.0 to 71.6) |
≥ 8 | 94 | 46.3 | 62.4 (53.9 to 70.4) | 90.3 (80.1 to 96.4) | 6.4 (3.0 to 13.9) | 0.4 (0.3 to 0.5) | 93.6 (86.6 to 97.6) | 51.4 (41.6 to 61.1) |
≥ 9 | 66 | 32.5 | 46.1 (37.7 to 54.7) | 98.4 (91.3 to 100.0) | 28.6 (4.0 to 201.0) | 0.6 (0.5 to 0.6) | 98.5 (91.8 to 100.0) | 44.5 (36.0 to 53.3) |