Figure 1

Unsupervised hierarchical clustering of 98 patients with septic shock (horizontal dimension) and 6,099 genes (vertical dimension) derived from a discovery-oriented filtering approach. Both the condition tree (patient clustering) and the gene tree are based on the Pearson correlation similarity measurement. The first- and second-order branching patterns of the condition tree were used to identify the putative septic shock classes and are colored for illustrative purposes based on three major putative septic shock subclasses.