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Table 10 Pancreatic cancer; meta-analysis results

From: Systematic review of the relation between smokeless tobacco and cancer in Europe and North America

     Heterogeneity
Type of ST (region)a Adjustments/restrictionsb Number of estimates (RR/OR ids)c Random-effects RR/OR (95% CI) χ2 I2 P2)
Any Overall data 7 (1, 5, 7, 11, 17, 18, 23) 1.00 (0.68–1.47) 18.5 67.5 0.005
  Smoking-adjusted 7 (1, 5, 7, 11, 16, 18, 23) 1.07 (0.71–1.60) 21.2 71.7 0.002
  Never smokers 5 (6, 10, 16, 18, 24) 1.23 (0.66–2.31) 10.7 62.7 0.030
Any (USA) Overall data 5 (1, 11, 17, 18, 23) 0.86 (0.47–1.57) 10.2 61.0 0.037
  Smoking-adjusted 5 (1, 11, 16, 18, 23) 0.99 (0.51–1.91) 13.8 71.0 0.008
  Never smokers 3 (16, 18, 24) 1.09 (0.44–2.67) 5.4 63.0 0.067
Snuff (Scandinavia) Overall data 2 (5, 7) 1.20 (0.66–2.20) 6.3 84.1 0.012
  Smoking-adjusted 2 (5, 7) 1.20 (0.66–2.20) 6.3 84.1 0.012
  Never smokers 2 (6, 10) 1.61 (0.77–3.34) 1.5 33.2 0.221
  1. a For each study/sex, the RR/OR for ST from Table 9 was included if available, otherwise that for chewing tobacco or snuff was used.
  2. b Smoking-adjusted includes estimates for smokers and non-smokers combined, adjusted for smoking if available, and estimates for never smokers otherwise.
  3. c The actual estimates included are identified by their RR/OR identification numbers as given in Table 9.
  4. CI = confidence interval; ST = smokeless tobacco; OR = odds ratio; RR = relative risk.