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Table 20 Bladder cancer; meta-analysis results

From: Systematic review of the relation between smokeless tobacco and cancer in Europe and North America

    

Heterogeneity

Type of ST (region)a

Adjustments/restrictionsb

Number of estimates (RR/OR ids)c

Random-effects RR/OR (95% CI)

χ2

I2

P(χ2)

Any

Overall data

14 (3, 4, 7, 8, 9, 12, 13, 16, 17, 18, 21, 22, 27, 31)

1.00 (0.80–1.25)

28.7

54.7

0.007

 

Smoking-adjusted

10 (3, 4, 8, 9, 12, 17, 21, 22, 27, 31)

0.95 (0.71–1.29)

22.3

59.6

0.008

 

Never smokers

6 (4, 8, 9, 21, 22, 28)

1.10 (0.60–2.02)

7.7

35.1

0.173

Any (USA)

Overall data

9 (7, 8, 9, 12, 13, 16, 21, 22, 27)

1.11 (0.85–1.45)

14.8

45.9

0.064

 

Smoking-adjusted

6 (8, 9, 12, 21, 22, 27)

1.24 (0.83–1.85)

10.4

52.1

0.064

 

Never smokers

5 (8, 9, 21, 22, 28)

1.25 (0.69–2.26)

5.6

29.2

0.227

Snuff (Scandinavia)d

Overall data

1 (3)

0.83 (0.62–1.11)

--

--

--

 

Smoking-adjusted

1 (3)

0.83 (0.62–1.11)

--

--

--

  1. a For each study/sex, the RR/OR for ST from Table 19 was included if available, otherwise that for chewing tobacco or snuff was used.
  2. b Smoking-adjusted includes estimates for smokers and non-smokers combined, adjusted for smoking if available, and estimates for never smokers otherwise.
  3. c The actual estimates included are identified by their RR/OR identification numbers as given in Table 19.
  4. d There are no data for never smokers for snuff in Scandinavia.
  5. CI = confidence interval; ST = smokeless tobacco; OR = odds ratio; RR = relative risk.