At baseline: | Â | Â | Â | Â |
---|---|---|---|---|
Variable | Normal | Micro | Macro | P value |
Sex (Male/Female) | 44 (29/15) | 46 (25/21) | 49 (25/24) | 0.3, ns |
Age (years) | 34 (20-72) | 35 (18-80) | 38 (21-79) | 0.09, ns |
Duration of diabetes | 11 (1-54) | 18 (1-65) | 25 (1-67) | <0.001 |
S. creatinine (μmol/l) | 74 (54-110) | 80 (42-175) | 103 (61-486) | <0.001 |
GFR (ml/min/1.73 m2) | 91(45-141) | 78 (28-144) | 60(9-105) | <0.001 |
Urine IgM (mg/mmol·10-3) | 6.7(1.7-31.8) | 8.7(2.5-40) | 11.5(2.8-363) | 0.009 |
HbA1c % | 7.6(4.5-13.4) | 8.8(5.5-13.2) | 9.1(6.2-12.7) | 0.01 |
ACEI/ARBs, n/n (%) | 0/0 (0%) | 3/3 (13%) | 15/5 (40.8%) | <0.001 |
MAP, mmhg | 92(78-110) | 96(80-127) | 103(82-133) | <0.001 |
During follow-up: | Â | Â | Â | Â |
Follow up time, years | 19(2-22) | 19(2-22) | 9(1-22) | 0.01 |
MAP, mmhg | 93(73-127) | 99(78-125) | 103(73-147) | 0.005 |
HbA1c % | 8.1(4.5-13.9) | 8.0(5.0-11.1) | 8.2(4.5-13.4) | 0.61 |
ACEI/ARBs, n/n (%) | 5/0 (11.4%) | 9/15 (53.3%) | 20/16 (76.6%) | <0.001 |
CV-Mortality rate per patient-year | 0.003994674 | 0.0110957 | 0.035836177 | <0.001 |
Renal failure rate per patient-year | 0 | 0.007407 | 0.032895 | <0.001 |