Skip to main content

Table 1 Characteristic of 139 patients with type 1 diabetes divided according to initial degree of albuminuria into normo (45), micro (46), and macro (48).

From: Increased urine IgM excretion predicts cardiovascular events in patients with type 1 diabetes nephropathy

At baseline:     
Variable Normal Micro Macro P value
Sex (Male/Female) 44 (29/15) 46 (25/21) 49 (25/24) 0.3, ns
Age (years) 34 (20-72) 35 (18-80) 38 (21-79) 0.09, ns
Duration of diabetes 11 (1-54) 18 (1-65) 25 (1-67) <0.001
S. creatinine (μmol/l) 74 (54-110) 80 (42-175) 103 (61-486) <0.001
GFR (ml/min/1.73 m2) 91(45-141) 78 (28-144) 60(9-105) <0.001
Urine IgM (mg/mmol·10-3) 6.7(1.7-31.8) 8.7(2.5-40) 11.5(2.8-363) 0.009
HbA1c % 7.6(4.5-13.4) 8.8(5.5-13.2) 9.1(6.2-12.7) 0.01
ACEI/ARBs, n/n (%) 0/0 (0%) 3/3 (13%) 15/5 (40.8%) <0.001
MAP, mmhg 92(78-110) 96(80-127) 103(82-133) <0.001
During follow-up:     
Follow up time, years 19(2-22) 19(2-22) 9(1-22) 0.01
MAP, mmhg 93(73-127) 99(78-125) 103(73-147) 0.005
HbA1c % 8.1(4.5-13.9) 8.0(5.0-11.1) 8.2(4.5-13.4) 0.61
ACEI/ARBs, n/n (%) 5/0 (11.4%) 9/15 (53.3%) 20/16 (76.6%) <0.001
CV-Mortality rate per patient-year 0.003994674 0.0110957 0.035836177 <0.001
Renal failure rate per patient-year 0 0.007407 0.032895 <0.001
  1. Abbreviations: ACEI: Angiotensin converting enzyme inhibitors; ARBs: Angiotensin II receptor antagonists; CV: cardiovascular; ESRD: End stage renal disease; GFR: glomerular filtration rate; HbA1c: glycosylated hemoglobin; MAP: Mean arterial blood pressure.