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Table 3 Characteristic of 139 patients with type 1 diabetes divided according to the median urine IgM level into low (<0.01 mg/mol) and high IgM (>0.01 mg/mol) groups.

From: Increased urine IgM excretion predicts cardiovascular events in patients with type 1 diabetes nephropathy

At baseline:    
Variable Low IgM group High IgM group P value
Sex (male/female) 71 (49/22) 68 (30/38) 0.003
Age (years) 35(18-74) 37(20-80) 0.05
Duration of diabetes (yr) 15 (1-65) 24 (1-67) 0.001
HbA1c % 8.3 (4.5-13.4) 9 (5.5-13.2) 0.06, ns
Albuminuria (mg/mmol) 3.6(0.23-268) 21.3 (0.26-640) <0.001
S. Creatinine μmol/l 78 (54-216) 86 (42-486) 0.009
GFR (ml/min/1.73 m2) 88 (27-141) 67(9-144) <0.001
MAP mmhg 93 (80-120) 100 (78-133) 0.004
ACEI/ARBs, n/n (%) 3/2 (7.1%) 15/6 (31%) <0.001
During follow-up:    
Follow up time (years) 19 (2-22) 14 (1-22) <0.001
MAP mmhg 97 (73-119) 103 (73-147) 0.038
HbA1c (%) 8.25 (4.5-13.9) 8 (4.5-13.4)  
0.7, ns    
Albuminuria (mg/mmol) 1.3 (0.1-676) 20.5 (0.1-1101) <0.001
ACEI/ARBs, n/n (%) 12/14 (37%) 22/17 (59%) 0.008
CV-Mortality rate per patient-year 0.005838 0.029104 <0.001
Renal failure rate per patient-year 0.003451 0.022161 0.003
  1. Abbreviations: ACEI: Angiotensin converting enzyme inhibitors; ARBs: Angiotensin II receptor antagonists; CV: cardiovascular; ESRD: End stage renal disease; GFR: glomerular filtration rate; HbA1c: glycosylated hemoglobin; MAP: Mean arterial blood pressure.