| TESI | TWOSI | 0.5 SD | ||||||
---|---|---|---|---|---|---|---|---|---|
 | OR | Pvalue | 95% CI | OR | Pvalue | 95% CI | OR | Pvalue | 95% CI |
Age (continuous) | 2.04 | 0.079 | 0.92 to 4.5 | 0.91 | 0.425 | 0.71 to 1.16 | 1.33 | 0.317 | 0.76 to 2.34 |
Age (categorical) | 6.57 | 0.149 | 0.51 to 36.75 | 0.83 | 0.629 | 0.39 to 1.77 | 1.14 | 0.452 | 0.81 to 1.59 |
Gender | 1.76 | 0.178 | 0.77 to 3.98 | 2.33 | 0.188 | 0.66 to 8.24 | 1.91 | 0.287 | 0.58 to 6.33 |
Randomisation status | 1.16 | 0.667 | 0.58 to 2.32 | 4.39 | 0.022 | 1.23 to 15.64 | 6.05 | 0.003 | 1.82 to 20.07 |
Drug (nortriptyline vs escitalopram) | 1.57 | 0.431 | 0.51 to 4.85 | 1.05 | 0.797 | 0.71 to 1.59 | 1.01 | 0.947 | 0.73 to 1.39 |
Observed mood dimension | 2.92 | <0.0001 | 1.92 to 4.46 | 3.28 | <0.0001 | 2.49 to 4.32 | 4.16 | <0.0001 | 3.24 to 5.35 |
Age at onset | 0.16 | 0.01 | 0.04 to 0.64 | 0.66 | 0.296 | 0.30 to 1.44 | 0.42 | 0.037 | 0.18 to 0.95 |
Number of episodes (more than 3) | 9.7 | 0.031 | 1.23 to 76.2 | 4.17 | 0.172 | 0.54 to 32.13 | 11.05 | 0.022 | 1.41 to 86.93 |
Duration | 0.95 | 0.291 | 0.86 to 1.04 | 1 | 0.325 | 0.99 to 1.01 | 1.01 | 0.065 | 0.99 to 1.02 |
Switchers | 2.2 | 0.022 | 1.11 to 4.35 | 5.94 | <0.0001 | 4.19 to 8.44 | 9.47 | <0.0001 | 6.57 to 13.6 |
Increasing dose | 2.03 | 0.92 | 0.44 to 9.48 | 1.31 | 0.269 | 0.81 to 2.11 | 1.42 | 0.184 | 0.85 to 2.37 |
Decreasing dose | 1.29 | 0.84 | 0.18 to 4.29 | 0.63 | 0.567 | 0.13 to 3 | 1.05 | 0.95 | 0.24 to 4.51 |
History of suicide attempts | 0.85 | 0.898 | 0.07 to 9.48 | 2.02 | 0.015 | 1.15 to 3.45 | 3.59 | <0.0001 | 2.31 to 5.58 |
Marital status | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Married/cohabiting | 4.66 | 0.017 | 1.32 to 16.42 | 0.73 | 0.285 | 0.41 to 1.29 | 0.79 | 0.723 | 0.23 to 2.81 |
Separated/divorced | 0.24 | 0.065 | 0.05 to 1.09 | 1.24 | 0.516 | 0.64 to 2.42 | 0.81 | 0.771 | 0.19 to 3.44 |
Single | 0.38 | 0.162 | 0.11 to 1.47 | 2.02 | 0.094 | 0.88 to 4.58 | 1.85 | 0.507 | 0.31 to 11.28 |
Occupation | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Full-time work | 0.27 | 0.073 | 0.04 to 1.16 | 0.79 | 0.402 | 0.45 to 1.38 | 0.31 | 0.062 | 0.11 to 1.09 |
Part-time work | 1.71 | 0.725 | 0.09 to 18.03 | 1.14 | 0.754 | 0.51 to 2.52 | 1.51 | 0.631 | 0.28 to 8.17 |
Unemployed | 6.84 | 0.002 | 2 to 23.3 | 0.75 | 0.323 | 0.41 to 1.33 | 1.82 | 0.337 | 0.53 to 6.29 |
Retired | 0.93 | 0.96 | 0.08 to 9.58 | 3.25 | 0.009 | 1.33 to 7.92 | 9.28 | <0.0001 | 4.61 to 18.72 |
Student* | - | - | - | 1.06 | 0.929 | 0.32 to 3.46 | 0.33 | 0.398 | 0.02 to 4.34 |
Children (yes vs no) | 1.04 | 0.978 | 0.05 to 21.43 | 0.57 | 0.124 | 0.29 to 1.16 | 0.49 | 0.378 | 0.11 to 2.33 |
Education | 1.12 | 0.504 | 0.79 to 1.59 | 0.95 | 0.264 | 0.87 to 1.04 | 0.91 | 0.358 | 0.76 to 1.11 |
Gender by drug interaction | Â | <0.0001 | Â | Â | <0.0001 | Â | Â | <0.0001 | Â |
Drug among men (nortriptyline vs escitalopram) | 9.83 | 0.01 | 1.72 to 56.27 | 2.47 | 0.004 | 1.34 to 4.56 | 3.51 | <0.0001 | 1.92 to 6.39 |