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Table 3 OXTR promoter CpG methylation status in peripheral blood mononuclear cells (PBMCs) and cortex samples of males

From: Genomic and epigenetic evidence for oxytocin receptor deficiency in autism

Site AutD cases (95%CI), (n = 10) Controls (95%CI), (n = 10) t Test
PBMCs:    
-860 41.0% (28.4 to 53.7) 13.8% (6.6 to 21.0) 0.0008
-901 48.1% (33.6 to 62.7) 36.9% (19.1 to 54.7) 0.3153
-924 71.1% (59.4 to 82.8) 59.3% (40.8 to 77.8) 0.2604
-934 58.7% (39.4 to 78.1) 19.8% (3.2 to 36.4) 0.0029
-959 48.6% (39.5 to 57.6) 41.7% (27.5 to 55.9) 0.3522
Cortex:    
-860 38.8% (5.4 to 72.2) 14.9% (3.6 to 26.2) 0.1208
-901 47.1% (13.1 to 81.2) 13.3% (3.6 to 23.0) 0.0508
-924 64.3% (30.6 to 98.0) 26.6% (7.2 to 46.1) 0.0375
-934 61.0% (24.4 to 97.5) 19.4% (1.1 to 37.7) 0.0320
-959 20.5% (8.0 to 32.9) 19.4% (1.1 to 37.7) 0.9032
  1. Bold text indicates a significant result by Satterthwaite test; %, percentage methylated. Cases and controls were all male.
  2. CI = confidence interval; AutD = autism disorder.